For structured outputs generation, I feel like Instructor is better and the API is simpler.

For prompt optimization, DSPy is better. I have a course on that by the way: https://www.lycee.ai/courses/a5b088fa-8a9f-4240-b57b-2b03463df84d/chapters/bab08b2c-972c-499d-933e-5afb877d1a4b